Anti-cancer drugs are also called anti-neoplastic agents or chemotherapeutic agents. They act upon rapidly dividing cancer cells and destroy them. They can be used single-drug therapy or combination therapy. Different kinds of anti-cancer drugs are alkylating agents (mechlorethamine, chlorambucil, etc.), Antimetabolites (methotrexate, gemcitabine etc.), Anti-microtubule agents (vinblastine, paclitaxel etc.), Topoisomerase inhibitors (etoposide, doxorubicin etc.), Cytotoxic agents (bleomycin, mitomycin etc.). They have severe adverse effects like hair loss,loss of appetite, nausea and vomiting, anemia, weight loss, etc.